The strongest human hybrids in One Piece

Humans are one of the most common and weakest races One piece. However, some tend to have a lot of power, with well-trained and refined individuals still having powerful powers in their own right. However, there are some people who have historically bred with other races, which leaves their offspring with more natural strength than they would otherwise have had.

Although it is unclear if these hybrids are superior or inferior to their counterparts, strength wise, there are some who are very skilled as warriors, carving as some of the the strongest characters within the larger series.

5 Dellinger

Fish-Human/Human Hybrid

• Affiliate: Donquixote Pirates; Diamond Army
• Parentage: Unclear, mixed human/fish ancestry
• Devil Fruit: None

Dellinger is a high-ranking member of the Donquixote Pirates, effectively inducted into the “family,” which includes its highest-ranking members. He is also a human who is a fish fighter. The already somewhat obscure nature of the fish's heritage is further complicated by Dellinger's lack of known parents. He was found orphaned by his team and raised by Giolla, a family member, who was responsible for his upbringing. This has influenced the style of Dellinger, such as high heels, which he wears and weapons.

Even at a young age, he was a full member of the team, which only took a few years to take over Dressrosa. As an adult, Dellinger is still a tough opponent to face. Human's relatively weak teeth hide a series of fighting fish, which helps him in his powerful movements. Like Arlong, he seems to be able to grow and lose his teeth at will, although the extent to which he can do so is still unclear. He was able to knock out participants in the Corrida Colosseum with little effort, including the likes of Ideo, Blue Gilly, and Sulieman. This puts him above even some members of the Straw Hat Grand Fleet. However, Hakuba, Cavendish's evil alter-ego, manages to defeat him with a single strike.

4 Charlotte Amanda

Snakeneck/Human Hybrid

• Connection: Big Mom Pirates
• Parents: Unknown Snakeneck (Father), Charlotte Linlin (Human Mother)
• Devil Fruit: None

Amande is from the Snakeneck Tribe, a race that has yet to be found outside of Totto Land. He is an officer of the Big Mom Pirates. All the known members of the group so far are human hybrids, and Linlin's children. Amande has three sisters who are fully related, as well as three snakeneck siblings along with many others of different races.

Although the rank of officers in Charlotte's siblings is common, Amande is designated as one of the more powerful siblings of the Vinsmoke family members. It turns out that he killed several soldiers to collect eggs. His limited screen time places him adept at his chosen sword, a Meito (famous or “great” sword) known as Shirauo.

3 Charlotte Smoothie

Longleg/Human Hybrid

• Affiliation: Big Mom Pirates; Three Sweet Bearers
• Parents: Unknown Longleg (Father), Charlotte Linlin (Human Mother)
• Devil Fruit: Shibo Shibo no Mi

Smoothie is from the Longleg Tribe and Linlin's daughter, and thus a member of the Big Mom Pirates.

The race is known for its long and strong legs, which usually enjoy show and decoration. In addition to her two sisters, Citron and Cinnamon, Smoothie also shares this distinction with Tamago, a team fighter, who is considered pure long-legged and unrelated to the Charlotte family.

Smoothie is not shown using his legs in battle, instead preferring to use the Shibo Shibo no Mi, which allows him to drain and absorb the juices of other living beings. He carries an unnamed large sword that stores juice inside, to be used as a projectile when needed. He also knows how to use two haki. In addition to his abilities, Smoothie is more distinguished as one of the Three Sweet Commanders, the three most powerful pirates in the crew besides their captain. He shares this distinction with Charlotte Katakuri, a pirate who was able to confront Luffy.

2 Most of the Seraphim

Lunarian/Human Hybrids

• Affiliation: Formerly Vegapunk, now World Government
• Parents: King (Genetic Ancestor), Ancient Warrior (templates), Vegapunk (Creator)
• Devil Fruit: None. Green blood allows anyone to have Paramecia powers

These cyborgs are a new breed of Pacifista created by Vegapunk. They resembled the seven warriors of the sea in their youth. The first difference is that each has a moon gene, from the King of Pirates Beasts, taken during the test in Punk Hazard. Considering that most of the Warlords are human,​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​most-honest, most of these Pacifistas can be classified as human hybrids. The human hybrids are S-Snake and S-Hawk, who are descended from Boa Hancock and Dracule Mihawk.

S-Bear technically counts as well, but he also has Buccaneer ancestry, thanks to being taken from Kuma. S-Shark, Jimbei's neighbor, is the only non-human hybrid in the series. Crocodile's three allies, Gecko Moria, and Donquixote Doflamingo, are also active at the moment. Judging from the naming conventions, they are likely to be called S-Crocodile, S-Gecko and S-Flamingo.

Seraphim was considered by Marine Admiral Issho to be able to replace the fighters, and restore the balance of power that had been lost by their elimination. This was partially proven when they were able to fight the likes of Blackbeard and the Straw Hat Pirates, both known to be among the current threats to the World Government. Being partially biological, they can age and become stronger than they are now.

1 Bartholomew Kuma

Buccaneer/Human Hybrid

• Group: Revolutionary Army (former), Seven Seas Fighters (former)
• Parents: Clapp (Buccaneer Father), Unnamed Human Mother
• Devil Fruit: Nikyu Nikyu no Mi

Bartholomew Kuma was a kind soul who used his powers to protect those he cared for. His terrible childhood as a slave, hunted for being part of the deeply persecuted buccaneer race, drove him to care for others who could not defend themselves. At times he acted like a priest, a revolutionary, and a king, but he always remained kind at all events. He is the real surrogate father of Bonney, who is in love with his mother Ginny, who gave birth to him in captivity as a slave of the World Noble. He wanted to protect Bonney, even at great cost to himself.

So he transforms into a Pacifist, planning a mission to protect the Thousand Sunny, before becoming an independent group. Meanwhile, Kuma is shown in a brief career as the Straw Hats, and remains a formidable fighter. The situation is enhanced by the Nikyu Nikyu no Mi-ny, which allows the air to explode, and transmits physical pain to people and from each other. After the destruction of the Seven Warlords of the Sea, Kuma was once again enslaved by the World Nobles, who took advantage of his resistance to pain. After being rescued by Sabo and the four revolutionary officers, Kuma is in a vegetative state. However, he managed to “hang in” and gain some form of independence, which Vegapunk credits to his buccaneer heritage. He was last seen meeting Bonney, after he and Luffy fought Saturn.

The true nature of the buccaneers as a race is unclear. They are a race of giants, although few have been seen but are not as tall as some of the “giant” humans, like Big Mom, who only have human heritage (as far as we know.) The father of is unknown. Kuma, Clapp's parents. That is why it is not clear how many giant ancestors there are. However, they are both known as buccaneers. The race is said to have committed a “serious sin”, although it has not yet been revealed.